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In specific embodiments, osmolarity/osmolality of the present formulations or compositions is adjusted, for example, by the use of appropriate salt concentrations (e.g., concentration of potassium salts) or the use of tonicity agents which renders the formulations or compositions endolymph-compatible and/or perilymph-compatible (i.e

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Controlled Release 2015, 206 , 49 57, DOI: 10.1016/j.jconrel.2015.02.027Google Scholar140Remote control of the permeability of the blood-brain barrier by magnetic heating of nanoparticles: A proof of concept for brain drug deliveryTabatabaei, Seyed Nasrollah
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