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In conclusion, our data suggest that the treatment with the antioxidant peptide Epitalon enhanced impaired wound healing processes in HG-injured ARPE-19 cells by inhibiting hyperglycemia-induced EMT and fibrosis, thus supporting the therapeutic benefits of this interesting peptide for DR management

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ROS-induced epithelial-mesenchymal transition in mammary epithelial cells is mediated by NF-B-dependent activation of Snail

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10.1172/jci.insight.122490 44 GrimmingerF.GntherA.VancheriC

The original data set was split into a training set (80% of the samples) and a test set (20% of the samples) prior to any step of statistical analysis