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Berberine Effects in Pre-Fibrotic Stages of Non-Alcoholic Fatty Liver DiseaseClinical and Pre-Clinical Overview and Systematic Review of the Literature

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One mechanism detail worth knowing: repeated high doses can blunt the response over time (desensitization), which is part of why dosing near the saturation point, not above it, is the common approach

doi: 10.2165/00007256-200333050-00003 44