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Mitochondrial dysfunction, including systemic deficiency of the electron transport chain complex I, is a well-established player in the pathogenesis of both sporadic and familial PD [96,97,98]

3HAA reduced measurable H 2 O 2 in a concentration-dependent manner (Fig

Possible defects that may lead to B 12 deficiency are listed in the right column of Table 1 [1,2,3]

Figure 10 shows that GSH deficiency ( GCLC -KD) caused a simultaneous increase in TNF- and decrease in VDR/PGC-1/GLUT-4 mRNA expression in GCLC -KD C2C12 myotubes (Fig

The "effective dose" in a 250-gram rat does not translate directly to a dose for an 80-kilogram human