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Furthermore, the preference of glycolysis over OXPHOS results in a reduction of ROS generation, which in combination with increased stress defense mechanisms, results in extended cell survival with maximal safeguard from genome instability ( 4 Mitochondrial physiology during reprogramming and differentiation Cellular reprogramming requires extensive mitochondrion architectural reorganization and metabolic shift to balance the need for pluripotency and self-renewal
2016, 173 , S10S15
Chicago, IL: McGraw-Hill, pp
10.1002/uog.19084 63 KiciskaA
Divicine and isouramil are aglycones that are highly reactive and produce ROS in the blood
M., De Souza, M
