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Consequently, the principal endpoint was not achieved

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The actions of cytosolic glutaredoxins (GRX) or cytosolic and mitochondrial thioredoxins (TRX1 and TRX2) restore the oxidized proteins back to their reduced state

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doi: 10.1128/MCB.10.5.2327 44 HeinrichPCBehrmannIHaanSHermannsHMMller-NewenGSchaperF

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