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Cells were then gently washed with Dulbeccos phosphate-buffered saline (DPBS) to remove serum-containing media and treated with peptide 2012, peptide 2020, or defactinib in triplicate replicates

In recent phase II clinical trials, azacitidine or decitabine was applied for three or five consecutive days in a 28-day cycle, exhibiting satisfactory therapeutic efficacy and tolerable safety

Kadia T, Ma H, Zeng K, Nighimoto M, Lye M, Huang M, Yilmaz M, DiNardo C, Issa G, Parmar S, Iyer S, Hari P, Daver N, Jabbour E, Borthakur G , Verstovsek S