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According to their investigative report dated Jan

We found that removal of the R4 amino group was tolerated, as the corresponding analog 23 (R4 = H) exhibited an IC 50 value of 0.07 M and an EC 50 value of 2.3 M

Lpez-Bermejo A, Khosravi J, Corless CL, Krishna RG, Diamandi A, Bodani U, Kofoed EM, Graham DL, Hwa V, Rosenfeld RG

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Therefore, more high-quality studies are needed to confirm the potential health benefits of camu camu

Furthermore, an inverse association between dietary copper intake and depression was observed to be more relevant in women than in men (Thi Thu Nguyen et al., 2019