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Vitamin E and human diseases Severe deficiency of vitamin E is relatively rare and occurs in individuals suffering from fat malabsorption syndromes characterized by insufficient absorption of dietary fats containing fat-soluble vitamin E (Traber 2014)

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Ferroptosis is an iron-dependent controlled cell death caused by polyunsaturated fatty acid-containing phospholipids (PL-PUFA) in cell membranes that differentiates from other types of cell death by iron-dependent accumulation of lipid peroxides and redox imbalance (3)

The field uses the ratio in research contexts to characterise tissues, to compare metabolic states, to follow experimental interventions