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In the dermaroller monotherapy group, female participants experienced a more significant reduction in the GB index, decreasing from a baseline mean of 19 (SD = 5) to 15 (SD = 5) at the final visit

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Jutel M, Akdis M, Akdis C

Multifunctional mitochondrial Epac1 controls myocardial cell death

After the treatment, we collected the microglia-conditioned media and performed cytokine profiling or ELISA assays to measure the levels of key pro-inflammatory cytokines and mediators such as TNF-, IL-1, and iNOS