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144 Beyond these effects on CAFs in carcinomas, TGF- has been shown to promote growth of other tumor types such as gliomas through the induction of autocrine and paracrine secretomes

These act as cofactors for enzymes that convert glutathione back to its reduced form

A review on steroidal 5-reductase inhibitors for treatment of benign prostatic hyperplasia

As an E3 ubiquitin ligase, FBXO22 mediates the proteasomal degradation of multiple substrates

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Cancer initiation and progression have been linked to oxidative stress through mechanisms that increase DNA mutations or induce DNA damage, genome instability, and cell proliferation 82
