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Description
R., Yanes O., Northen M
No GLUT-1 inhibitor is currently available for use in humans ( Interference with the NADH/NAD + ratio is possible by interference with the polyol pathway by zopolrestat, an inhibitor of aldose reductase, which converts sorbitol to fructose
It targets GLP-1, GIP, and glucagon receptors , making it a triple agonist
In addition, GSTM3 overexpression combined with IR treatment resulted in a marked increase in the signal level of 4-HNE (181,182)
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