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In another study on rat hearts, addition of both insulin and KB to isolated perfused working rat hearts led to a 35% increased efficiency of cardiac hydraulic work (98)

Subsequently, this copper is directed towards lysosomes and is eventually excreted into the bile, thereby maintaining homeostasis and preventing copper overload

My interpretation of the emerging data is that both of these components have to work together

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Li, F., Hu, Z., Huang, Y
