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Two-trial social defeat stress In this paradigm, the test mouse (intruder) was introduced into the home cage of a larger, retired breeder male CD1 mouse (67 months of age, 4045 g) for 2 min, during which it was subjected to physical aggression (defeat) by the resident mouse

Additionally, 15 of the included studies focused on B12 supplementation, with a total of 5,191 participants (mean: 346 per study)

Saini S, Hindmarsh PC, Matthews DR, Pringle PJ, Jones J, Preece MA, Brook CG