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Moreover, MDSCs facilitate neovascularization through different mechanisms

In response to herbivorous insect attack or wounding at local leaves, wound signaling molecules are released at the damaged plant cells, and may bind corresponding receptors to trigger propagation of slow wave potentials (SWPs) 6,7,8,9 , initiate transmission of cytoplasmic calcium ([Ca 2+ ] cyt ) 10,11,12,13,14,15 , and consequently activate biosynthesis of defensive phytohormone jasmonic acid (JA), thereby mediating expression of defense-responsive genes for systemic defense responses in plants 7,8,11,12,16,17,18

After 18 weeks, the authors discovered that the antioxidants in the fruit turned on antioxidant defense pathways, which ultimately increased the activity of genes that boost the production of glutathione