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30 Three of the four RCTs of B12 alone used oral B12 (1000 g per day) and one used i.m

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The metabolism and elimination of NAD+ (and its by-products) could be altered in advanced hepatic or renal dysfunction, and high-dose NAD+ might theoretically affect cardiovascular dynamics, so practitioners generally avoid or closely supervise NAD+ use in such settings

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This protocol is not suitable for people who do not absorb the vitamin well for any reason (macro doses should be used)

Weeks Two Through Four Energy levels and recovery speed show the most noticeable regression during this period