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[DOI] [PMC free article] [PubMed] [Google Scholar] Han Lyn, F

Research Mechanism (Mechanism of Action) NNMT normally catalyses the transfer of a methyl group from S-adenosylmethionine (SAM) to nicotinamide, producing 1-methylnicotinamide (1-MNA)
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Neuroreport 5(5):593596 Iversen L, Mulvihill E, Haldeman B, Diemer NH, Kaiser F, Sheardown M, Kristensen P (1994) Changes in metabotropic glutamate receptor mRNA levels following global ischemia: increase of a putative presynaptic subtype (mGluR4) in highly vulnerable rat brain areas

Dallas, Tex 36 (3), 430435
ABSTRACT There is significant evidence that the pathogenesis of several neurodegenerative diseases, including Parkinsons disease, Alzheimers disease, Friedreichs ataxia and amyotrophic lateral sclerosis, may involve the generation of reactive oxygen species and mitochondrial dysfunction
