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Excessive ROS production has been demonstrated to directly interact with cellular biomolecules, including DNA, lipids, and proteins ( 10 )

Cisplatin-induced DNA damage activates replication checkpoint signaling components that differentially affect tumor cell survival

, Patrick, K

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Methionine enters cells via different methionine transporters (like SLC1A5, SLC7A5, SLC7A8, SLC7A6, SLC7A7, SLC38A1, and SLC38A2) [30]

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