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Further, this elevated ICAM-1 expression has been shown to activate neutrophils and endothelial cells, as evidenced by F-actin polymerization and increased accumulation of neutrophils within the lung microcirculation [80,81,82]

The bis-allylic hydrogen atoms in PUFA-PLs (bond dissociation energy ~88 kcal/mol) are highly susceptible to OH-induced abstraction, triggering a self-amplifying lipid peroxidation chain reaction

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