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The designed peptide (referred to as VGB4) was able to bind to both VEGFR1 and VEGFR2 on the Human Umbilical Vein Endothelial Cells (HUVECs) surface and inhibited VEGF-A driven proliferation, migration and tube formation in HUVECs through suppression of ERK1/2 and AKT phosphorylation

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Additionally, high doses of folic acid (exceeding 0.1 mg per day) may result in hematologic remission in patients with vitamin B12 deficiency

5mg/2ml