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Since 5HT is a powerful vasoconstrictor (29), a smooth muscle mitogen (30), and cardiovascular instability is associated with acute MDMA lethality (31), we used 1 H-MRS and HPLC to determine the effect of MDMA on the cardiac metabolic profile and monoamine levels in rats treated with MDMA

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10.1016/j.cell.2017.01.013 [DOI] [PMC free article] [PubMed] [Google Scholar] Waterhouse M, Risch HA, Bosetti C, Anderson KE, Petersen GM, Bamlet WR, Cotterchio M, Cleary SP, Ibiebele TI, La Vecchia C, et al