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(See Figure 4 for overall approach to treatment and prevention of gout.) Treatments used for prevention, such as allopurinol (see below) can actually make things worse if given during a flare, and so need to be held back until the flare has resolved for several weeks

This highlights an important distinction between biological plausibility and clinical evidence

10.1038/s41598-020-72989-2
I would highly recommend perx and bpc-157

Most protocols recommend a 2 to 4 week break between cycles
