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12 mg remains the highest-efficacy dose, but it carries a meaningfully worse GI burden and a correspondingly higher dropout risk

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Watch for early warning signs such as: Dark-colored urine Dry mouth Fatigue Muscle cramps Headache Feeling lightheaded or dizzy Reduced performance during work or exercise The best way to stay ahead of dehydration is to drink fluids consistently throughout the day, replace electrolytes during prolonged sweating, take breaks in the shade or air conditioning, and recognize when symptoms require medical attention