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Despite conservation of the core fold among SLC6 transporters, subtype-specific structural features confer distinct functional profiles

Brain MDA or GSH were not significantly altered by fluoxetine, sertraline or imipramine alone (Figs
doi: 10.1016/j.ebiom.2020.102793 159 WagenblastESotoMGutirrez-ngelSHartlCAGableALMaceliARet al

Water without a buffer will cause pH to dramatically change so pH and TA must work together to find a balance

it neutralizes free radicals and maintains cellular homeostasis
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