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The 2026 Medicare payment reflects the CMS CY2026 Physician Fee Schedule Final Rule (CMS-1832-F), which established the updated conversion factor and RVU values effective January 1, 2026

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This proposal was supported by the essentially perfect correlation for binding affinity differences between the selected pair of compounds obtained by rigorous free energy perturbation calculations by Gutierrez-de-Terans group (Vanga et al., 2018)