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Although a recent trial has shown to be beneficial when antiviral treatment is introduced early during the disease before hospitalization than later in the course of the disease, there is an urgent need for early therapies to reduce the risk of disease progression, prevent transmission, and be widely distributed to meet the worldwide demand (Gottlieb et al., 2022

10.1007/s13311-020-00862-1 Neurotherapeutics 22 MeinN.von StackelbergN.WickelJ.GeisC.ChungH

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A second GSH allows for reduction of the Se-SG bond, and results in the restoration of the active site with the formation of oxidized glutathione (GSSG)