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D/L-glucose competition experiment To measure the competitive effects of CDr17 with D/L-glucose, the media of M1 macrophages differentiated from RAW264.7 cell was changed into DMEM, no glucose (Gibco) with 10% Heat-Inactivated Fetal Bovine Serum (Gibco) and 1% Penicillin Streptomycin (WELGENE), containing 0, 20, 60 mM of D/L-glucose

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N800 decreased the hepatic gene expressions of lipid transporter, lipid synthesis, and interferred -oxidation, leading to lipid accumulation and increasing Cyp2E1 expression, and finally, decreased ATP production

Muda P, Kampus P, Zilmer M, Zilmer K, Kairane C, Ristime T, et al

Aisen, P

SeyfferthALMorrisAHGillRKearnsKAMannJNPaukettMet al