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A Pcbp1-Bola2 chaperone complex delivers iron for cytosolic [2fe-2s] cluster assembly

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10.1039/d3tb00276d [DOI] [PubMed] [Google Scholar] Klontzas M

Curcumin Activates the Nrf2 Pathway and Induces Cellular Protection Against Oxidative Injury

Together, this evidence underscores how oxysterol-driven MAPK signaling can tip the balance toward neurodegeneration, with JNK and p38 activation overriding ERKs protective effects to promote apoptosis in neurons and glia