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Reveals by using FRET technology that a segment of the STIM1 C-terminal domain containing the active site undergoes an important intramolecular transition into an extended conformation upon interaction with Orai

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Patients were randomized to the study groups using simple randomization through a randomization table created by a computer software program

doi: 10.1016/j.pmpp.2015.01.003 126 Rodrguez-SerranoM.Romero-PuertasM

122 However, it was recently reported that Sorafenib could not induce ferroptosis by inhibiting System Xc - , thus it might not be a true ferroptosis inducer