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Hawkins, Zac

Serologic autoantibodies as diagnostic cancer biomarkersa review

ROS play an important role in microbial decontamination either directly by inducing oxidative stress or indirectly by promoting pathogen clearance through a number of non-oxidative mechanisms, including autophagy, T-cell responses, and pattern recognition receptor signaling 44

In general, untreated resistant cancer cells (namely, of colon and ovarian cancers) have been shown to exhibit a higher glycolytic activity directed towards lactic fermentation (Warburg effect) or the pentose phosphate pathway (PPP), leading to reduced oxidative phosphorylation (OXPHOS) [15,16,17]