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Intrinsic factor binds cobalamin only within the alkaline pH of the intestines

[DOI] [PubMed] [Google Scholar] 91.Hayano M., Yang W.S., Corn C.K., Pagano N.C., Stockwell B.R

Treatment of vitamin B(12)-deficiency anemia: oral versus parenteral therapy

Furthermore, whilst loss of C9orf72 in mice models disturbs microglial function, resulting in age-related neuroinflammation, this was not sufficient to cause neurodegeneration in C9orf72 knockout mice (Lall and Baloh, 2017)

For immunohistochemistry, post-excised kidneys were fixed with 4% paraformaldehyde, cryoprotected with 30% sucrose, and frozen embedded in OCT medium (TissueTek)
