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Immunology 142 (1), 2431

A comprehensive literature search was performed to identify recent reports investigating LUTS and OS in major chronic diseases

Zhang, Jiang et al., 2016

It is noteworthy that gene-nutrient interactions, especially between the C677T mutation of the MTHFR gene and folate status and perhaps between heterozygosity for CBS defect and folate status (Lentz et al, 2000), could be involved in the onset of hyperhomocysteinemia