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In addition, rather than leading to an increase in rT3 levels directly caused by an imbalance in DIO3, the available data imply that Se deficit may indirectly cause these levels to rise via reduced clearance of DIO1 and changes in peripheral thyroid hormone metabolism [33]

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10.1038/srep09102 335 ZhuC.LiJ.LiuC.ZhouP.YangH.LiB
