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Following cleavage by furin (between residues R307 and S308), pro-c-MET is converted into a mature heterodimer (mature c-MET) composed of an extracellular -chain and a single-pass transmembrane -chain linked by disulfide bonds [2][3]

Amylin and hypertension: association of an amylin-G132A gene mutation and hypertension in humans and amylin-induced endothelium dysfunction in rats

10.1016/0002-9343(94)90149-X

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