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M., Sheaff, M

B., Stehbens, W

& Surmeier, D
Even though the pathophysiology of these conditions is well understood, it has not been adequately translated into effective treatments to stop or reverse the course of the disease ( One of the key challenges in developing effective therapies against NDs is the blood-brain barrier (BBB) which is very selective hence, hinders the delivery of therapeutic agents to the brain ( Recent breakthroughs in nanotechnology have provided novel approaches for overcoming the BBB

10.1056/NEJM199403033300907 58 LiuH.DengY.GaoJ.LiuY.LiW.ShiJ.et al

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