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Trace elements have two purposes
Compared to fresh vegetables, folate content lessened by 10% in green bean cans (30% in beans alone, but most of the lost folate was retained in the covering liquid), mainly owing to the sterilization step with no significant impact of washing and blanching steps during the canning chain 397
This dual dysfunction of microglia and astrocytes leads to extensive oxidative stress, immune activation, and eventual neuronal degradation

Sci Rep 12(1):7716 Terrier B et al (2011) Low 25-OH vitamin D serum levels correlate with severe fibrosis in HIV-HCV co-infected patients with chronic hepatitis

Clin Interv Aging 9:637652

[CrossRef] [PubMed] 204
