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A study comparing bioavailability of crystalline B12 at different oral doses found that the body can only absorb about 1-1.2 mcg B12 via the gut per dose

The pH of GI tract varies from 1 7, with stomach pH between 13, duodenum pH between 6.06.5, and large intestine pH from 5.57.0 (Van de Graaff, 1986)

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If you are considering sublingual semaglutide instead, the semaglutide dosage charts and semaglutide mixing charts provide equivalent detail for that medication
