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Mitochondria are avid consumers of iron, using as much as 20-50% of total cellular iron depending on cell type [38,39]

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Dig Dis Sci 50:S24S33 Tewari D, Anjum N, Tripathi Y (2014) Phytochemistry and pharmacology of Plantago Ovata : a natural source of laxative medicine

Emerging studies now demonstrate that specific metabolic alterations directly fuel replication stress, DNA damage, and compromised DNA damage response