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doi: 10.1152/ajplung.00322.2018 67 ParpaleixAAmsellemVHoussainiAAbidSBreauMMarcosEet al

Mitochondrial DNA is a molecule of double-stranded DNA which binds to cyclic GMP-AMP synthase, an enzyme which converts ATP and GTP into 23-cyclic GMP-AMP

Scott, J

Growing evidence indicates that dysbiosis, immune activation, and IEB dysfunction have a role in several diseases, including irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), and gluten-related conditions

Some of the key roles of B12 in your body include: Helping in the normal functioning of the nervous system Playing a vital role in DNA synthesis B12 is among the vitamins needed in the breakdown of amino acids and fatty acids Helps in the creation and maturation of red blood cells (hemoglobin) in the bone marrow Supports the production of digestive enzymes and the delivery of essential nutrients to and from cells Its vital to the development of a fetus in pregnant women Having a deficiency in vitamin B12 can lead to several different symptoms, including fatigue, headaches, pale skin, anemia, vision issues, sores of the mouth/tongue, and even cognitive functioning changes

The free form of aspartate is also limited in this dietary model because it activates N-methyl-D-aspartate receptors