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In biofilms, the extracellular matrix formed by the cells themselves holds the groups of bacteria or multicellular communities together

In a mouse model of pancreatic cancer liver metastasis, the use of IGF-IR inhibitor IGF-Trap reshaped the local immunosuppressive microenvironment of liver tumors, reduced the recruitment of bone marrow-derived suppressor cells, reversed innate immune cell polarization and inhibited metastatic expansion

In vivo studies have shown that oral administration of aspirin significantly reduces tumor growth in BALB/c nude mice

Mol Cell Proteom 20:1000022 Neuzil J, Dyason JC, Freeman R, Dong L-F, Prochazka L, Wang X-F, Scheffler I, Ralph SJ (2007) Mitocans as anti-cancer agents targeting mitochondria: lessons from studies with vitamin E analogues, inhibitors of complex II

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13 , 104 , 106 In gellan-gum-based systems, the sol-gel transition forms a double helical junction zone in response to interactions with cations, especially calcium ions, in the nasal fluid