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Agramunt, J

Consequently, a lack of function of TREM2 has previously been linked to an increased risk of AD [100]

Numerous studies have shown that the C-terminal extension is required for membrane and/or particulate fraction binding, G q binding, and maximum basal and G q -stimulated activity (Park et al., 1993
doi: 10.1016/j.jplph.2005.10.002

It has been shown, that the NS4 expression altered the distribution of mitochondria and caused damage which leads to the host cell apoptosis[66]
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