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In glucose metabolism, ER, similar to ER, seems to enhance glycolysis while repress OXPHOS (213)

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14,362,363 Their findings revealed that TCA flux in primary solid tumors, such as pancreatic cancer, NSCLC, and CRC, was lower than in corresponding normal tissues, while in hematological malignancies like NOTCH1-driven T cell acute lymphocytic leukemia, TCA flux in the spleen was elevated compared to normal spleen tissue

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