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These insights have motivated the exploration of alternative strategies that preserve LNP stability and delivery efficiency while minimizing immunogenicity

GSH is found throughout cellular compartments in millimolar concentrations (110 mM)

In cell death, MG emerges as a key player, while elevated GLO I expression and activity act as saviors for drug-resistant tumor cells with high glycolytic rates [27]

Chuquet et al., According to this hypothesis, neurons meet their high energetic requirements by utilizing astrocyte-derived lactate (produced from extracellular glucose or glycogen pools), which can be oxidized in the TCA cycle following its conversion to pyruvate

[DOI] [PMC free article] [PubMed] [Google Scholar] 261.Zhao Y., Li J.S., Guo M.Z., Feng B.S., Zhang J.P
Simultaneous intrastriatal and intranigral fetal dopaminergic grafts in patients with Parkinson disease: a pilot study
