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Because its level in the blood is almost entirely dependent on the kidneys, it is a sensitive marker of renal function and is used to estimate GFR (Levey 1999)
Microchem J 147:10381047
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Mutation at the catalytic site of topoisomerase I in CEM/C2, a human leukemia cell line resistant to camptothecin
ROS plays a role in cancer progression, promoting various cellular processes despite causing mutagenesis
