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E11O0028 Product Name Bovine Oxidized Glutathione ELISA kit Species Bovine Product Size 48 Tests / 96 Tests Concentration 250-5000 pg/mL Sensitivity 1.0 pg/mL Principal Competitive ELISA Sample Volume 100 ul Sample Type Serum, plasma, cell culture supernatants, body fluid and tissue homogenate Assay Time 90 minutes Platform Microplate Reader Conjugate HRP Detection Method Colorimetric Storage 2-8C Kit Components MATERIALS SPECIFICATION QUANTITY MICROTITER PLATE 96 wells stripwell ENZYME CONJUGATE 6.0 mL 1 vial STANDARD A (0.5mL) 0 pg/mL STANDARD B (0.5mL) 250 pg/mL STANDARD C (0.5mL) 500 pg/mL STANDARD D (0.5mL) 1000 pg/mL STANDARD E (0.5mL) 2500 pg/mL STANDARD F (0.5mL) 5000 pg/mL SUBSTRATE A 6 mL SUBSTRATE B STOP SOLUTION WASH SOLUTION (100 x) 10 mL BALANCE SOLUTION 3 mL Principle of the Assay GSSG ELISA kit uses an anti-GSSG antibody and an GSSG-HRP conjugate in a competitive enzyme immunoassay method

Ferroptosis is characterised by increased reactive oxygen species (ROS), lipid peroxidation, iron accumulation, as well as depletion of glutathione (GSH) [47], and it has been seen in chronic bone disorders, such as OA [48-50]

Alzheimers Disease Increased oxidative stress, impaired folate metabolism, and mitochondrial dysfunction

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Bioenergetic insufficiencies due to metabolic alterations regulated by the inhibitory receptor PD-1 are an early driver of CD8 + T cell exhaustion