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Through laboratoryexperimentationon various animals, including rodents, pigs, dogs, and humans, the unique mechanism of AOD-9604 has been identified, which primarily stimulates the release of fat from adipose tissue, inhibits the accumulation of new fat in adipocytes, and promotes fat oxidation

Different investigations may utilize different formulations, dosing approaches, or treatment durations, making it challenging to compare results across studies and establish optimal therapeutic protocols

The majority of the published literature examines each compound independently, and the synergy hypothesis, while mechanistically well-supported, has not yet been the subject of large-scale controlled studies