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10.1093/oxfordjournals.aje.a010000 60 KimG.KimH.KimK

In contrast with other studies, Errera et al

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Resveratrol inhibits cancer progression by regulating the process of autophagy and ferroptosis Resveratrol has been shown to induce autophagy and ferroptosis in lung, breast, pancreatic, ovarian cancers, as well as myeloma, leading to cell death and tumor growth inhibition [829, 830].It activates key autophagy-associated proteins, such as Beclin-1 and LC3, which promote the degradation of damaged organelles and proteins [831,832,833], as well as increasing the phosphorylation of AMPK and decreasing the phosphorylation of mTOR and its downstream substrates in a dose-dependent manner, leading to autophagy [832]