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Shayna Sandhaus, PhD Table of Contents Overview Introduction General Background Development of Heavy Metal Toxicity Common Heavy Metal Toxicants and Associated Health Risks Risk Factors for Toxic Metal Exposure Heavy Metal Testing and Toxicity Signs & Symptoms Conventional Treatment Novel & Emerging Therapies Lifestyle Management for Reducing Metal Toxicity Risk Nutrients Update History References 1 Overview Summary and Quick Facts for Heavy Metal Detoxification Acute heavy metal intoxications may damage central nervous function, the cardiovascular and gastrointestinal systems, lungs, kidneys, liver, endocrine glands and bones

All authors discussed the literature base and finally read and approved the final manuscript

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Integrated analysis of microbiome and transcriptome reveals the mechanisms underlying the chlorogenic acid-mediated attenuation of oxidative stress and systemic inflammatory responses via gut-liver axis in post-peaking laying hens

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