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Overall, we found that CAR T cells in post-infusion BM samples from LTR have high levels of mTOR signaling, high metabolic polyfunctionality, and an effector immunometabolic profile, and that the BM microenvironmental milieu of LTR may promote mTOR activity for improved anti-tumor activity

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1 But that doesnt make it natural

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Some research 2 has suggested that women on oral contraceptive pills should supplement with DHEA in order to restore testosterone levels in the body