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Science 317 , 9499 (2007) Schmidt, H

Recurrence rates are high when the root cause goes unaddressed

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H.HuitingaI.MeliefJ.et al

Second-line treatments, known as device-aided therapies (DATs), have been developed for LDRCs, such as continuous subcutaneous apomorphine infusion (CSAI), continuous subcutaneous foslevodopafoscarbidopa, infusion of levodopacarbidopa intestinal gel (LCIG entacapone) and subthalamic deep brain stimulation